Age-associated b cells are long-lasting effectors that impede latent γhv68 reactivation

HIGHLIGHTS

• who: Isobel C. Mouat from the CentreUniversity of have published the Article: Age-associated B cells are long-lasting effectors that impede latent u03b3HV68 reactivation, in the Journal: Scientific Reports Scientific Reports

SUMMARY

The authors found that during acute γHV68 infection (6 days p.i.), roughly 40% of ABCs in the spleen expressed IFNγ and TNF, as compared to about 10% of ABCs in naïve mice (Fig 2A,B). During latent infection (35 days and 150 days p.i.), a significantly increased proportion of ABCs continued to express IFNγ and TNF compared . . .

 



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