Age-associated global dna hypermethylation augments the sensitivity of hearts towards ischemia-reperfusion injury

HIGHLIGHTS

  • who: DNA et al. from the University of California, Irvine, United States have published the paper: Age-associated global DNA hypermethylation augments the sensitivity of hearts towards ischemia-reperfusion injury, in the Journal: (JOURNAL)
  • what: The authors evaluated the cardiac response of young and adult rat hearts to I/R injury from the perception of DNA methylation, one of the key epigenetic modifiers in I/R.
  • how: The basal tissue level global DNA methylation changes of adult and young sham hearts were measured and the results are given in Figure 2. To understand . . .

     

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