Age-dependent effects of gut microbiota metabolites on brain resident macrophages

HIGHLIGHTS

  • who: Thomas Blank from the University of Bern, Switzerland have published the research: Age-dependent effects of gut microbiota metabolites on brain resident macrophages, in the Journal: (JOURNAL)
  • how: In a rat model similar observations were made when treatment with TMAO raised pre-operative and postoperative plasma levels of TMAO which exacerbated microgliamediated neuroinflammation (Meng et_al 2019).

SUMMARY

    The molecular and cellular markers of aging in mammals have been established at a fundamental level (LópezOtín et_al, 2013), but they are associated with shifts in the microbiome, impacting the pace . . .

     

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