Age-linked suppression of lipoxin a4 associates with cognitive deficits in mice and humans

HIGHLIGHTS

• who: Fabricio A. Pamplona from the Study design and ethics All mouse experiments were performed under protocols approved and supervised by the Institutional Animal Care and Use Committee of Federal University of Rio de Janeiro (CEUA-UFRJ) (protocol noIBQM058). The sample size for each experiment was estimated by performing pilot studies and by previous experience with different experimental approaches. No algorithm or software was used to randomize animal subjects. Animal subjects were assigned to experimental groups by the researchers. Experiments with animal samples were performed in a blinded fashion. Experimental procedures involving human clinical data and CSF . . .
  

   

  

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