Aggrecan governs intervertebral discs development by providing critical mechanical cues of the extracellular matrix

HIGHLIGHTS

• who: . and colleagues from the Universitu00e4t Ulm, Germany The University of Hong Kong, China have published the paper: Aggrecan governs intervertebral discs development by providing critical mechanical cues of the extracellular matrix, in the Journal: (JOURNAL)
• what: The authors report the generation of an insertional Acan mutant mouse line and describe the consequences of ACAN deficiency on vertebral column and intervertebral disc development. The reason of this discrepancy is not known. The authors obtained high-resolution AFM images on native tissue cryo-sections, which may better preserve and visualize the collagen network (Graham et_al, 2010 . . .
  

   

  

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