Aging

HIGHLIGHTS

• who: Zhenghua Su et al. from the School of Pharmacy, Pharmacophenomics Laboratory, Human Phenome Institute, Zhangjiang Fudan International of Bioactive Small Molecules, Fudan University, Shanghai, PRChina have published the research: AGING, in the Journal: (JOURNAL)
• what: The authors aim to address the effects of Smyd2 on regulating angiotensin II (Ang II)-induced vascular endothelial cells (VECs) senescence and its epigenetic mechanism. The authors focused on Smyd2, which can mono-methylate histone 3 lysine 4 (H3K4me1), was profoundly upregulated in Ang II-induced VECs, and Smyd2 ablation attenuated senescence-associated phenotypes both in_vitro and in_vivo. The . . .
  

   

  

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