Aging

HIGHLIGHTS

• who: Ya-Jen Chiu and collaborators from the Department of Life Science, National Taiwan Normal University, Taipei, Taiwan have published the research: AGING, in the Journal: (JOURNAL)
• what: The authors explored if LM-031 analogs LMDS-1 to -4 may act as TRKB agonists to protect SH-SY5Y cells against Au03b2 toxicity. The authors identified novel potential TRKB agonists with good bioavailability .
• how: These results indicated that the LM-031 and analogs not only hindered the aggregation of amyloid but also attenuated oxidative stress caused by Au03b2 overexpression. Consistent with these previous reports . . .
  

   

  

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