HIGHLIGHTS
- who: OS and colleagues from the Department of Orthopedics, Jincheng People`s Hospital, Jincheng, Shanxi Province, China have published the article: AGING, in the Journal: (JOURNAL)
- what: As part of the present study, the authors investigated the underlying biochemical mechanisms of ZCCHC12 and its impact on osteosarcoma.
- how: The results showed that ZCCHC12 knockdown resulted in decreased PI3K and AKT phosphorylation while ZCCHC12 overexpression strongly promoted their phosphorylation .
SUMMARY
Meanwhile, the authors found that osteosarcoma cells may be induced to proliferate and migrate by ZCCHC12. ZCCHC12 enhanced OS cells . . .
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