HIGHLIGHTS
- who: Victoria C. Brom from the Weizmann Institute of Science, Israel University of L`Aquila, Italy have published the research: Agonistic and antagonistic targeting of immune checkpoint molecules differentially regulate osteoclastogenesis, in the Journal: (JOURNAL)
- what: Because the function of these immunomodulatory co-receptors is highly cell-type specific and the role of macrophages as osteoclast precursors is widely published, the authors aimed to analyze the effect of immune checkpoint inhibitors on these bone-resorbing cells. To the standardization of experimental analyses involving osteoclasts, the study has revealed the substantial effects of agonistic and antagonistic . . .
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