Agonistic anti-dcir antibody inhibits itam-mediated inflammatory signaling and promotes immune resolution

HIGHLIGHTS

  • Who: Agonistic anti-DCIR antibody inhibits and collaborators from the Massachusetts, USA have published the article: immune resolution, in the Journal: (JOURNAL)
  • Future: To address this limitation future studies can explore the application of a bispecific agonistic antibody design to cluster DCIR with another immune inhibitory receptor such as PD-1 or utilize engineered Fc regions to enhance cross-linking with FcγIIB.

SUMMARY

    Immune regulator receptors play a crucial role in immune homeostasis by balancing activating versus inhibitory immune_responses. This fine-tuned regulation from 2 opposed signaling modules can be . . .

     

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