Agr2-associated er stress promotes adherent-invasive e. coli dysbiosis and triggers cd103+ dendritic cell il-23-dependent ileocolitis

HIGHLIGHTS

• who: Monica Viladomiu from the Jill Roberts Institute USA Cornell University have published the research work: Agr2-associated ER stress promotes adherent-invasive E.u00a0coli dysbiosis and triggers CD103+ dendritic cell IL-23-dependent ileocolitis, in the Journal: (JOURNAL) of November/15,/2022
• what: The authors show that AIEC, but not SFB, is associated with Th17 responses that exacerbate disease and promote ileocolitis in an AGR2-deficient background, highlighting the requirement for ER stress and potentially other factors in shaping pathogenic Th17 cell activation in this model .
• how: To evaluate if these CD103 . . .
  

   

  

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