HIGHLIGHTS
- who: Lydia Kuhnert and colleagues from the Institute of Pharmacology, Pharmacy and Toxicology, Faculty of Veterinary Medicine, and, of Padua, Agripolis Legnaro (Padua), Italy have published the Article: AhR-activating pesticides increase the bovine ABCG2 efflux activity in MDCKII-bABCG2 cells, in the Journal: PLOS ONE of 23/Dec/2019
- what: This study proposes an in_vitro MDCKII-bABCG2 cell model for identifying AhR-activating and bABCG2-inducing pesticides, implementing the 3R principle in practice.
- how: The study subsequently used the cell model to asses thirteen pesticides approved for use in the European Union . . .
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