Ahr activation leads to attenuation of murine autoimmune hepatitis: single-cell rna-seq analysis reveals unique immune cell phenotypes and gene expression changes in the liver

HIGHLIGHTS

• who: Alkeiver S. Cannon et al. from the Harvard Medical School, United States Michigan State University have published the article: AhR Activation Leads to Attenuation of Murine Autoimmune Hepatitis: Single-Cell RNA-Seq Analysis Reveals Unique Immune Cell Phenotypes and Gene Expression Changes in the Liver, in the Journal: (JOURNAL)
• what: In the current study, therefore, the authors investigate by using TCDD, the role of AhR activation on a murine model of hepatitis. This study reported an increase in immune Th17/Treg balance toward the immunotolerant Treg phenotype in a variety of inflammatory disease models . . .
  

   

  

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