Aid and apobecs span the gap between innate and adaptive immunity

HIGHLIGHTS

  • who: Arnaud Moris from the Center for Immunology and Microbial Infections, Faculty of Medicine, Université Paris-Sorbonne, UPMC Univ, France, University of Nantes have published the research: AID and APOBECs span the gap between innate and adaptive immunity, in the Journal: (JOURNAL)
  • how: In this study the authors propose that the cellular DNA-repair machinery activates DNAdamage- and stress-response pathways in response to uraciledited HIV DNA leading to the up-regulation of activating NK cell ligands (NKG2D ligands) and killing of HIV infected cells.

SUMMARY

    The structure of AID/APOBEC . . .

     

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