Aiding cancer’s “sweet tooth”: role of hexokinases in metabolic reprogramming

HIGHLIGHTS

  • who: Zeenat Farooq and collaborators from the Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, The University of Illinois at Chicago, Chicago, IL, USA have published the Article: Aiding Canceru2019s u201cSweet Toothu201d: Role of Hexokinases in Metabolic Reprogramming, in the Journal: Life 2023, 946 of /2023/
  • how: This review describes the role distribution and regulation of different isoforms and their metabolic functions in cancer.
  • future: Interestingly HK3 responds towards G6P and Pi similarly to HK2 which supports an anabolic role for HK3 further research is needed to answer this question . Future Directions . . .

     

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