Aim2 as a putative target in acute kidney graft rejection

HIGHLIGHTS

  • who: Nathu00e1lia Franchon Marques Tejada from the Center, United States South University, China have published the research: AIM2 as a putative target in acute kidney graft rejection, in the Journal: (JOURNAL)
  • what: The analysis indicated allograft rejection, interferon, and inflammatory response as the main processes positively regulated for the AIM2 phenotype, while oxidative_phosphorylation (OXPHOS) and fatty_acid metabolism were most negatively regulated (Supplementary Table 1). Considering that allograft rejection and OXPHOS were the main regulated pathways for both the AIM2 phenotype and acute rejection group and that the current literature supports intracellular metabolism as a potential . . .

     

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