Akt and sgk kinases regulate cell migration by altering scar/wave complex activation and arp2/ 3 complex recruitment

HIGHLIGHTS

  • who: TYPE et al. from the Queen Mary University of London, United Kingdom have published the Article: AKT and SGK kinases regulate cell migration by altering Scar/WAVE complex activation and Arp2/ 3 complex recruitment, in the Journal: (JOURNAL)
  • what: The authors report that PKB and PkgB regulate Scar/WAVE phosphorylation and pseudopod formation in Dictyostelium.
  • how: The experimental groups were tested for normal distribution using the Shapiro-walk test of Prism 7 software Cells were lysed by directly adding NuPAGE LDS sample buffer (Invitrogen) containing 20 mM DTT HALT protease and phosphatase . . .

     

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