Akt isoforms in the immune system

HIGHLIGHTS

  • who: Mireia Guerau-de-Arellano from the National Institute of Arthritis and (NIH), United States Medical University of South Carolina have published the article: Akt isoforms in the immune system, in the Journal: (JOURNAL)
  • what: Much of the work on Akt in macrophages focuses on the in_vitro-generated extreme phenotypes M1 and M2. The priming also depends on the activity of Akt and represents a potential strategy that can be employed to enhance the effectiveness of NK cell killing in cancer immunotherapy. This study showed that hyperlipidemia selectively activates Akt2 in Tregs and that Akt2 . . .

     

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