Akt/pacs2 participates in renal vascular hyperpermeability by regulating endothelial fatty acid oxidation in diabetic mice

HIGHLIGHTS

  • who: CPT and colleagues from the Health Management Center, Third Xiangya Hospital of Central South University, Changsha, China, Department of Cardiology have published the research work: AKT/PACS2 Participates in Renal Vascular Hyperpermeability by Regulating Endothelial Fatty Acid Oxidation in Diabetic Mice, in the Journal: (JOURNAL)
  • what: The authors evaluated the regulation of vascular endothelial metabolism and its role in DN.
  • how: The authors evaluated whether AKT works upstream of PACS2 in HUVECs treated with HGHF. The results showed that PA-OCR was significantly reduced after HGHF exposure. This result was consistent with . . .

     

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