Akt phosphorylation as a predictive biomarker for pi3k/mtor dual inhibition-induced proteolytic cleavage of mtor companion proteins in small cell lung cancer

HIGHLIGHTS

• who: Ming-Chun Hung from the Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Keyan Road, Zhunan, Miaoli County, Taiwan have published the paper: AKT phosphorylation as a predictive biomarker for PI3K/mTOR dual inhibition-induced proteolytic cleavage of mTOR companion proteins in small cell lung cancer, in the Journal: (JOURNAL)
• what: These results suggest the level of can be companion diagnostic biomarker for the treatment of SCLC involving the combinational use of clinically approved isoform-specific PI3K and mTOR inhibitors. u2020 and contributed equally to this work Institute of Biotechnology and Pharmaceutical . . .
  

   

  

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