Alcohol consumption, blood dna methylation and breast cancer: a mendelian randomisation study

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SUMMARY

    The World Cancer Research Fund (WCRF) examined the association between alcohol drinking and breast cancer based on existing literature, and concluded that there was strong evidence for a causal role of alcohol intake in postmenopausal breast cancer and probable evidence in premenopausal breast cancer, with an additional risk of 9% per 10 g/day increase in alcohol consumption. A pooled analysis identified positive associations between alcohol consumption and the risk of breast cancer subtypes regardless of the status of two hormone_receptors (i.e., estrogen receptor, ER; progesterone receptor, PR), and there was no significant . . .

     

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