Aldh1-mediated autophagy sensitizes glioblastoma cells to ferroptosis

HIGHLIGHTS

  • who: Yang Wu and collaborators from the Department of Neuropathology, Institute of Pathology, School of Medicine, Technical University Munich, Munich, Germany have published the article: ALDH1-Mediated Autophagy Sensitizes Glioblastoma Cells to Ferroptosis, in the Journal: Cells 2022, 11, x FOR PEER REVIEW of /2022/
  • what: Since both and ferroptosis interact with lipid peroxidation (LPO) the authors aimed to investigate a possible connection between and ferroptosis. The authors show that RSL3-induced LPO and ferroptotic cell death revealed RSL3-sensitive and -resistant malignant glioma cell lines.
  • how: The results showed that ALDH1a3 knockout . . .

     

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