HIGHLIGHTS
- who: Jaime Ibarrola from the Adult male Wistar rats were treated for , weeks with vehicle (n=10), Aldo-salt (Sigma, mg/kg per day and, % NaCl as drinking water have published the research work: Aldosterone Impairs Mitochondrial Function in Human Cardiac Fibroblasts via A-Kinase Anchor Protein, in the Journal: (JOURNAL)
- what: This study shows that Aldo-induced oxidative stress could be mediated by AKAP-12 down-regulation that leads to PGC-1u03b1 reduction and to mitochondrial dysfunction.
SUMMARY
The authors have recently identified AKAP-12 as a down-regulated protein . . .
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