Aldosterone inhibits dot1l expression in guinea pig cochlea

HIGHLIGHTS

• who: Shixun Zhong from the Twenty-eight adult guinea pigs weighing, g, with normal Preyer`s reflex, were divided randomly into two groups, in each groupAldosterone (A9477, Sigma, American) , mg/kg/d was injected intraperitoneally in animals of the treatment group and , u03bcl saline was injected in those of the control group for , days [8, ]. Animals were killed under deep anesthesia by intraperitoneal pentobarbital sodium solution (, mg/kg) , month later. Six animals in each group were used for histopathology and immunohistochemistry, and the others for Western blot analysis. The animals were provided by the experimental animal research . . .
  

   

  

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