Alignment of human kat2a (gcn5) histone acetyltransferase and sars-cov-2 orf8 viral proteins

HIGHLIGHTS

  • who: Posted Date November et al. from the (UNIVERSITY) have published the paper: Alignment of human KAT2A (GCN5) Histone Acetyltransferase and SARS-CoV-2 Orf8 viral proteins, in the Journal: (JOURNAL)

SUMMARY

    The SARS-CoV-2 virus has evolved to mimic an enzyme, KAT2A (lysine acetyltransferase 2A, GCN5), one of the histone proteins that package DNA in the cell nucleus. The Orf8 protein from the SARS-CoV-2 virus also has an ARKS motif. Using structures from RCSB Protein Data Bank, the authors examined another way that Orf8 may interfere with KAT2A. SARS . . .

     

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