Alk-positive histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to alk inhibition

HIGHLIGHTS

  • who: MYELOID NEOPLASIA et al. from the DepartmentLeiden University have published the research work: ALK-positive histiocytosis: a new clinicopathologic spectrum highlighting neurologic involvement and responses to ALK inhibition, in the Journal: Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY of 05/07/2022
  • what: Criteria for a diagnosis of ALKpositive histiocytosis and inclusion in the study were the following: histologic confirmation of a histiocytosis with expression of at least 2 macrophage/histiocyte markers (including CD163, CD68, CD14, and/or CD4) by the lesional cells and_(2A) molecular confirmation of ALK rearrangement and/or . . .

     

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