HIGHLIGHTS
- who: Weijian Wang from the Huazhong University of Science and Technology, Wuhan, China have published the paper: ALKBH5 prevents hepatocellular carcinoma progression by post-transcriptional inhibition of PAQR4 in an m6A dependent manner, in the Journal: (JOURNAL)
- what: The authors focused on the top 6 downregulated genes: ISG15, HERC6, SYT14, PAQR4, TAP1, and FYB1 (Fig 2B). In the research , it was shown that ALKBH5 expression was related to the decreased m6A methylation level of PAQR4, which led to decreased PAQR4 mRNA stability. Interestingly, the study showed that a higher expression level of PAQR4 was detected . . .
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