All roads lead to heterogeneity: the complex involvement of astrocytes and microglia in the pathogenesis of alzheimer`s disease

HIGHLIGHTS

  • who: Marie-u00c8ve Tremblay from the University of Oxford, United Kingdom have published the Article: All roads lead to heterogeneity: the complex involvement of astrocytes and microglia in the pathogenesis of Alzheimer`s disease, in the Journal: (JOURNAL)

SUMMARY

    Alzheimer`s disease (AD), the most common form of dementia, is a neurodegenerative disease notably associated with severe synaptic loss and brain atrophy, clinically resulting in cognitive decline (Terry et_al, 1991; Spires-Jones and Hyman, 2014; Pini et_al, 2016; Halliday, 2017; Marino et_al, 2019). Several key brain regions (e_g, hippocampus, dentate gyrus, entorhinal cortex . . .

     

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