Allele-specific analysis reveals exon- and cell-type-specific regulatory effects of alzheimer’s disease-associated genetic variants

HIGHLIGHTS

• who: Liang He from the (UNIVERSITY) have published the paper: Allele-specific analysis reveals exon- and cell-type-specific regulatory effects of Alzheimeru2019s disease-associated genetic variants, in the Journal: (JOURNAL) of 12/08/2021
• what: To discover novel eQTLs across more brain regions and further explore their cell-type-specific cis-regulatory effects, in this work, the authors focused on interrogating single nucleotide polymorphisms (SNPs) identified in GWAS of LOAD and conducting an allelespecific eQTL (aseQTL) analysis in four regions in the cerebrum using 3000+ tissue and cell-sorting bulk RNA-seq samples and . . .
  

   

  

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