Alloreverse: multiscale understanding among hierarchical allosteric regulations

HIGHLIGHTS

  • who: Jinyin Zha et al. from the State Key Laboratory of Functions and Applications of Medicinal Plants and School of Pharmacy, Medical, China, Medical, China, Medicinal Chemistry have published the Article: AlloReverse: multiscale understanding among hierarchical allosteric regulations, in the Journal: (JOURNAL)

SUMMARY

    Allostery is the phenomenon that the function of an orthosteric site is regulated by a topologically distant allosteric_site. Allostery is a fundamental way to tune the life process and has been applied manually for the treatment of human diseases, namely designing drugs bound to allosteric_sites to realize a ‘remote control . . .

     

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