Allosteric regulation of g-protein-coupled receptors: from diversity of molecular mechanisms to multiple allosteric sites and their ligands

HIGHLIGHTS

  • who: Alexander O. Shpakov from the Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences have published the research work: Allosteric Regulation of G-Protein-Coupled Receptors: From Diversity of Molecular Mechanisms to Multiple Allosteric Sites and Their Ligands, in the Journal: (JOURNAL) of 24/03/2023
  • what: Estimation of the number and localization of allosteric_sites in each receptor is a very difficult task, although significant progress in this direction has been made due to the development of new approaches for the identification of GPCR allosteric_sites .
  • how: The first allosteric regulators . . .

     

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