Allostery inhibition of bace1 by psychotic and meroterpenoid drugs in alzheimer’s disease therapy

HIGHLIGHTS

• who: Samuel C. Ugbaja et al. from the Discipline of Medical Biochemistry, School of Laboratory Medicine and Medical Science, University of have published the research: Allostery Inhibition of BACE1 by Psychotic and Meroterpenoid Drugs in Alzheimeru2019s Disease Therapy, in the Journal: Molecules 2022, 27, x FOR PEER REVIEW of /2022/
• what: The authors assess changes to the BACE1 backbone structure when bound to compound 1 using RMSD calculation of the protein Cu03b1 atoms. As a sequel to the previous review study on some identified allosteric inhibitors and exosite-binding antibodies of BACE1 over the last . . .
  

   

  

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