HIGHLIGHTS
- who: Joachim Greilberger and collaborators from the Division of Medical Chemistry, Otto Loewi Research, Medical University of Graz, Graz, Austria have published the Article: Alpha-Ketoglutarate or 5-HMF: Single Compounds Effectively Eliminate Leukemia Cells via Caspase-3 Apoptosis and Antioxidative Pathways, in the Journal: (JOURNAL)
- what: The combination of aKG and 5-HMF definitely reduces oxidative modifications, which are a hallmark in carcinogenesis and tumoral growth, including downregulation of antioxidative substances and antioxidative regulating enzymes of the Krebs cycle in the mitochondria but also in the cytosol.
- how: The Jurkat cell line . . .
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