Alpha subunit-dependent glycine receptor clustering and regulation of synaptic receptor numbers

HIGHLIGHTS

  • who: A. Patrizio from the (UNIVERSITY) have published the research: Alpha subunit-dependent glycine receptor clustering and regulation of synaptic receptor numbers, in the Journal: (JOURNAL) of 17/05/2017
  • what: In this approach the number of molecules within a complex is determined by counting spatially and temporally separated bursts of detections arising from single fluorophores.
  • how: To determine a possible role of the α subunit in GlyR clustering the authors compared the assembly of α1 and α3 containing GlyRs and their accumulation at synapses using a single molecule counting approach based on photoactivated . . .

     

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