Alpha-synuclein: the spark that flames dopaminergic neurons, in vitro and in vivo evidence

HIGHLIGHTS

  • who: Alexandre Henriques et al. from the Neuro-Sys, In Vitro Pharmacology Department, Gardanne, France have published the Article: Alpha-Synuclein: The Spark That Flames Dopaminergic Neurons, In Vitro and In Vivo Evidence, in the Journal: (JOURNAL)
  • what: To test this hypothesis, the authors aimed to prevent cell entry of α‐syn by blocking The authors aimed to investigate the effect of α-syn injections in the SNpc of 18-month-old mice, combined with a chronic inhibition of GBA.
  • how: The authors hypothesized that impairing applied a covalent inhibitor of GBA on the primary . . .

     

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