Alpha4 beta7 integrin controls th17 cell trafficking in the spinal cord leptomeninges during experimental autoimmune encephalomyelitis

HIGHLIGHTS

  • who: Barbara Rossi from the East Tennessee State University, United States have published the Article: Alpha4 beta7 integrin controls Th17 cell trafficking in the spinal cord leptomeninges during experimental autoimmune encephalomyelitis, in the Journal: (JOURNAL)
  • what: The authors investigated the roles of a4 integrins in the migration of Th1 and Th17 cells, two cell populations involved in the induction of autoimmunity and neuroinflammation during EAE .
  • how: The authors obtained results showing a reduction of wall shear stress (WSS) at disease peak compared to healthy mice and other disease conditions further supporting an altered . . .

     

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