Alphafold predicted structure of the hsp90-like domains of the neurodegeneration linked protein sacsin reveals key residues for atpase activity

HIGHLIGHTS

• who: Hypothesis and colleagues from the University of North Carolina at Chapel Hill, United States have published the article: AlphaFold predicted structure of the Hsp90-like domains of the neurodegeneration linked protein sacsin reveals key residues for ATPase activity, in the Journal: (JOURNAL)
• what: The authors propose that a unique piece of structure, as part of the HSP-N-terminal Repeat
• how: The authors investigated the lid`s dynamics through clustering analysis of the entire MD trajectory. To investigate the motions of the loop in the simulations the authors carried out clustering analysis . . .
  

   

  

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