Alteration of pd-l1 (sp142) status after neoadjuvant chemotherapy and its clinical significance in triple-negative breast cancer

HIGHLIGHTS

• What: The authors aimed to investigate the effects of NAC on (SP142) status and its clinical significance in TNBC. In the current study, 182 pairs of TNBC tissue samples before and after NAC were analyzed for PD-L1 (SP142) expression. The study demonstrated the predictive value of positive PD-L1 status (both SP142 and 22C3) for pCR after NAC, in accordance with previous studies .
• Who: Ji Won Woo from the Department of Pathology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Gumi‑ro , Beon‑gil, Bundang‑gu, Seongnam, Gyeonggi, Republic of Korea . . .
  

   

  

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