Alterations in homologous recombination-related genes and distinct platinum response in metastatic triple-negative breast cancers: a subgroup analysis of the profiler-01 trial

HIGHLIGHTS

  • who: Elise Bonnet and colleagues from the Department of Medical Oncology, Centre Lu00e9on Bu00e9rard, France have published the paper: Alterations in Homologous Recombination-Related Genes and Distinct Platinum Response in Metastatic Triple-Negative Breast Cancers: A Subgroup Analysis of the ProfiLER-01 Trial, in the Journal: (JOURNAL)
  • how: The authors analyzed data from mTNBC patients enrolled in the ProfiLER-01 study to determine the prevalence of alterations in recombinationrelated (HRR) and their association with sensitivity.
  • future: Studies are needed regarding the impact of HRR-genes in mTNBC and their predictive impact regarding sensitivity . . .

     

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