HIGHLIGHTS
- who: Antonio Rodriguez-Calero from the University of Bern, Bern, Switzerland have published the research: Alterations in homologous recombination repair genes in prostate cancer brain metastases, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: The authors comprehensively assess the genomic features which define PCBM. To provide insights into mutational processes specifically associated with metastasis to the brain the authors compare primary samples from this cohort to the large scale primary-PCa cohort from Given this enrichment in the PCBM cohort, the authors focused on alterations affecting at least one of the 15 homologous recombination repair . . .
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