Altered coronary artery function, arteriogenesis and endothelial yap signaling in postnatal hypertrophic cardiomyopathy

HIGHLIGHTS

• who: March et al. from the University of California, San Diego, United States have published the research work: Altered coronary artery function, arteriogenesis and endothelial YAP signaling in postnatal hypertrophic cardiomyopathy, in the Journal: (JOURNAL)
• what: To investigate early HCM progression, the authors focused on the onset of myofilament dysfunction during neonatal development and examined cardiac dynamics, coronary vascular structure and function, and mechano-transduction signaling in mice harboring a thin-filament HCM mutation. The study provides insights into the multiple pathological mechanisms involved in early HCM progression: early coronary flow and diastolic dysfunction, peri . . .
  

   

  

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