Altered differentiation and inflammation profiles contribute to enhanced innate responses in severe copd epithelium to rhinovirus infection

HIGHLIGHTS

  • who: Joseph C. Kidney from the University of Lausanne, Switzerland have published the research: Altered Differentiation and Inflammation Profiles Contribute to Enhanced Innate Responses in Severe COPD Epithelium to Rhinovirus Infection, in the Journal: (JOURNAL)
  • what: The authors investigated the impact of the innate host response and barrier function of severe COPD WDPBECs on HRV-induced innate immune_responses.
  • how: To address this the authors exploited a well-differentiated primary bronchial epithelial_cell (WD-PBEC) air-liquid interface (ALI) model to compare the phenotype of cultures from severe COPD patients with those from age-matched . . .

     

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