Alternative exon usage in trim21 determines the antigenicity of ro52/ trim21 in systemic lupus erythematosus

HIGHLIGHTS

• who: Eduardo Gomez-Bau00f1uelos et al. from the DivisionHopkins University of Rome, Rome, Italy have published the research: Alternative exon usage in TRIM21 determines the antigenicity of Ro52/ TRIM21 in systemic lupus erythematosus, in the Journal: (JOURNAL)

SUMMARY

Ro52, also known as tripartite motif-containing protein 21 (TRIM21), is an IFN-induced E3 ubiquitin ligase that drives negative-feedback regulation during inflammation and has also been identified as a cytosolic antibody receptor involved in the intracellular clearance of antibody-coated viruses, such as adenovirus. Initially described as part of the Ro antigenic particle . . .

 



If you want to have access to all the content you need to log in!

Thanks :)

Username or Email

Password

Remember me

Lost your password?

If you don't have an account, you can create one here.