Alternative polyadenylation transcriptome-wide association study identifies apa-linked susceptibility genes in brain disorders

HIGHLIGHTS

  • who: Ya Cui from the (UNIVERSITY) have published the research work: Alternative polyadenylation transcriptome-wide association study identifies APA-linked susceptibility genes in brain disorders, in the Journal: (JOURNAL) of 28/02/2022
  • what: As an example, the authors focused on ATXN3 in ALS, as ATNX3 3u2032aQTLs showed the highest colocalization probability with the ALS GWAS signal (PP4=0.969, Supplementary Table 2), but not with ATNX3 eQTLs (Fig 5e, f).
  • how: The results showed that the lead PD GWAS SNP rs356203 has a very significant 3u2032aQTL signal but no eQTL signal which . . .

     

    Logo ScioWire Beta black

    If you want to have access to all the content you need to log in!

    Thanks :)

    If you don't have an account, you can create one here.

     

Scroll to Top

Add A Knowledge Base Question !

+ = Verify Human or Spambot ?