HIGHLIGHTS
- who: Huihao Tang from the InstitutShanghai University have published the research: Alternative signal priming enhances the inflammatory response in macrophages, in the Journal: (JOURNAL) of 31/01/2023
SUMMARY
Macrophages can undergo multiple alternative activation states in response to various stimuli, such as transforming growth factor β (TGFβ), interleukin 10 (IL-10), and chitin. The next question is whether such a synergistic effect occurs in general or is restricted to IL-4-induced alternative activation. Macrophage metabolism affects their activation and function. The acquisition of an alternative phenotype is accompanied by a dramatic shift . . .
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