Alzheimer blood biomarkers: practical guidelines for study design, sample collection, processing, biobanking, measurement and result reporting

HIGHLIGHTS

• What: To help address these issues the authors provide fundamental guidelines developed according to recent research findings on the impact of sample handling on blood biomarker measurements. While the authors focus on the key blood-based AD biomarkers for the AT(N) criteria (e_g amyloid-beta 40 Aβ42 Aβ42/40 ratio total-tau phosphorylated-tau neurofilament light chain brain-derived tau and glial fibrillary acidic protein) the authors anticipate that these guidelines will generally be applicable to other types of blood biomarkers. It is important to note that the choice of the blood specimen depends . . .
  

   

  

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