Amanita muscaria extract potentiates production of proin ammatory cytokines by dsrna-activated human microglia

HIGHLIGHTS

  • who: TYPE and collaborators from the Oregon Health and Science University, United States have published the paper: Amanita muscaria extract potentiates production of proin ammatory cytokines by dsRNA-activated human microglia, in the Journal: (JOURNAL)
  • what: The authors show, for the first time, that HMC3 are activated by TNF and poly(I:C), but not substance P, to produce IL-6 and IL-8. Lastly, the authors show that trehalose, an autophagy inducer, and a major component of A. muscaria extract, also significantly potentiated IL-8 production by poly(I:C) activated HMC3. The authors . . .

     

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