Amf-26, a novel inhibitor of the golgi system, targeting adp-ribosylation factor 1 (arf1) with potential for cancer therapy*

HIGHLIGHTS

• who: Yoshimi Ohashi from the (UNIVERSITY) have published the research: AMF-26, a Novel Inhibitor of the Golgi System, Targeting ADP-ribosylation Factor 1 (Arf1) with Potential for Cancer Therapy*, in the Journal: (JOURNAL) of October/25,/2011
• what: The authors focused on the activation of ADP-ribosylation factors (Arfs) by its guanine nucleotide exchange factors (GEFs). Molecular Dynamics Simulation for Model Refinement-To refine the model of the Arf1-AMF-26-Sec7 domain complex, AMBER 9 was used for further minimization and MD simulations on 7 nodes of an Appro 1122Hi (AMD Opteron 248 . . .
  

   

  

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