Amino acid transporter lat1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and vegf-a-dependent mtorc1 activation

HIGHLIGHTS

• who: Lili Quan from the Department of Bio-system Pharmacology, Graduate School of Medicine, Osaka University, Yamadaoka, Suita, Osaka, Japan have published the research: Amino acid transporter LAT1 in tumor-associated vascular endothelium promotes angiogenesis by regulating cell proliferation and VEGF-A-dependent mTORC1 activation, in the Journal: (JOURNAL)
• what: The authors aimed to establish the upregulation of LAT1 as a novel general characteristic of tumor-associated endothelial cells as well and to explore the functional relevance in tumor angiogenesis. The authors demonstrate the LAT1 expression is upregulated in tumorassociated blood vessels but not in . . .
  

   

  

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