Aminooxy click modification of a periodate-oxidized immunoglobulin g: a general approach to antibody-drug conjugates with dye-mediated expeditious stoichiometry control

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  • who: Ksenia A. Sapozhnikova and collaborators from the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya, Moscow, Russia Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory, Moscow, Russia have published the paper: Aminooxy Click Modification of a Periodate-Oxidized Immunoglobulin G: A General Approach to Antibody-Drug Conjugates with Dye-Mediated Expeditious Stoichiometry Control, in the Journal: (JOURNAL)
  • what: The authors aimed to further study the scope of applicability of this approach. The authors report the synthesis of oxime-linked anti-PRAME ADCs that have cyanine dyes into expeditious their structure introduced for monitoring . . .

     

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